The researchers at the SNM’s 55th Annual Meeting have declared to invent the method to track the location and activity of mesenchymal stem cells (MSCs) in the tumors of living organisms. Thus the method is thought to be a major step towards cancer treatment. The scientists Use the noninvasive molecular imaging technology for the method.
MSCs are adult stem cells with the ability to transform into many different types of cells, such as bone, fat or cartilage. Scientists believe that stem cells show great promise in treating different types of diseases. A few stem cell therapies are already used to fight some types of cancer. The transplant, if proved successful, will enable the stem cells to migrate to the patient’s bone marrow and begin producing healthy cells that will replace the cancer cells. For other types of cancer, researchers are experimenting with modifying stem cells that could be engineered to deliver chemotherapy more precisely to specific tumor sites.
Hui Wang, a postdoctoral fellow was the lead researcher of the study. Wang and her team isolated stem cells from adult mice and engineered a reporter gene that would be both luminescent and green under a special microscope. The study produced solid evidence that the injected stem cells migrate to the tumors and don’t begin to differentiate into other types of cells until they are at the tumor sites. In some of the mice, the breast cancer cells had begun to spread to the lungs. Researchers found that the injected stem cells also migrated to the lung cancer tumors. In addition, the stem cells that migrated to lung tumors differentiated into bone cells, while the stem cells that migrated to breast cancer tumors differentiated into fat cells.
“Stem cell cancer therapies are still in the early stages of development, but they offer great promise in delivering personalized medicine that will fight disease at the cellular level,” said Hui Wang, the lead researcher of the study.
Source: The Science Daily