Angsuman Chakraborty12 Feb 2009 07:36 am
A huge score of U.S. population suffer from the dreaded chronic degenerative disorder named Multiple Sclerosis (MS). Problems in vision and speech, feeling weak in the muscles are its primary symptoms.What happens inside the body? Nothing much, only our central nervous system degenerates slowly due to destruction of myelin in spinal cord and brain.
Jokes apart, it can really make your and your family’s life a hell. Such was the life of Edwin McClure, just 4 years ago. This star football player was a patient of MS.
Then he participated in a clinical trial conducted by researchers at Northwestern University to study effect of stem cell transplantation on multiple sclerosis. It became a huge success.
Patients own stem cells were stimulated to grow more cells. After chemo treatment harvested stem cells were transplanted back into the patients.
The treatment lasted nearly month. Finally, McClure was successfully cured of the demyleination problem.
Incurable Multiple sclerosis once again conquered by emerging stem cell therapy.
Wow! this is the original breakthrough.
Source:The Early Show
Filed under Adult Stem Cell, Advocacy, Cancer, Multiple Sclerosis, Stem Cell | 2 Comments
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2 Responses
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February 12th, 2009 at 5:45 pm
My husband has MS and we have been following this research very closely. If this therapy does help to reverse the effects of MS and bring about a permanent remission, we would be truly grateful. We’re watching and waiting to find out more.
April 18th, 2009 at 4:38 pm
Dear Sir,
My young friend is having MS for last 4 years and we are surfing the net for the possible cure. Do you mind sharing your experience of the treatment as we too, are looking into the possibility of Stem cells. As we reside in India, could you help us out with the other centres, if you know..or can we part of the blog or the MS group, so that we can get the regular updates…Her medical history, I have narrated below…Hoping to have your reply and hope we can communicate often to crystalize our thoughts
Medical history:
Facial palsy of right side in 1996
Hypothyroidism since 1998. taking 100 micrograms of thyroxine daily.
Oct 2005 had weakness in legs and had difficulties walking. right leg had motor power loss and left had sensory loss.
Invesitigations: MRI of brain and spine showed demylinating areas esp in periventricular areas and some in spine. Lumber puncture showed oligoclonal bands positive.
given 5 days of 1000mg IV steroids and physiotherapy.
diagnosed as probable Multiple Sclerosis
Recovered 95 % of motor power but not sensory loss
Jan 2008 Similar to the first attack this time recovery of motor power was about 90 % and no sensory recovery.
five day course of IV steroids.
June 2008 right leg and hands (neck downwards) had motor loss and left sided sensory loss.
Recovery in upper trunk and limbs About 90% motor power regained in right arm with sensory loss recovery about 85 - 90 % on the left side. The right leg gained about 75% of its motor power and regained 50-60% sensory loss on the left which had occured in the first attack.
Given 5 day course of IV steroids.
Nov 2008 both lower limbs affected with motor power loss.followed by 85% recovery with five day steroid course.
Feb 2009 both lower limbs had motor power loss and severe tingling sensations. The tingling still continues till present day and she has phases where the tingling increases affecting her walking and balance for about an hour till the tingling subsides. This happens about 3 - 5 times a day. The motor power recovery has been about 70%.
Over this period her fatigue levels have also increased.
She is currently started with interferons and taken 4 injections, once weekly ( Avonex - Beta interferon 30 Microgrms IM)
The MRI has been done once a year and has showed increase in the number of lesions in the spine and brain.
There is no other neurological involvement of the eyes, speech, swallowing and breathing.
Currently She is back to work and can still manage to drive the car.
Hope, to hear from you soon..
With regards,
Jyoti Shah, MD