Harvard Researchers produced live mice by using sperm-like cells derived from embryonic stem cells. This research may someday help lead to new treatments for infertility.
The breakthrough marks the first time researchers produced healthy offspring from sperm cells fostered in a different species. The hope is this method could help generate sperm from endangered species or prize bulls.
Reproductive biologist Takashi Shinohara at Kyoto University in Japan and his colleagues first began with rats genetically engineered to produce a green fluorescent protein. Their cells and progeny would thus prove easy to recognize. Shinohara and his colleagues then removed the stem cells that sperm arise from in the rats and implanted them into testicles of mice.