Researchers from Northwestern University have shown that children with high-risk acute lymphocytic leukemia (ALL) receiving umbilical cord blood transplants have similar outcomes to patients receiving related allogeneic stem cell transplants.研究人員從美國西北大學已表明,兒童與高風險的急性淋巴細胞白血病( ALL )接受臍血移植手術也有類似的結果,以病人接受有關的異基因造血幹細胞移植。 The details of this comparative study were presented at the Third Annual International Umbilical Cord Blood Transplantation Symposium in Los Angeles, Calif., June 3-4, 2005.詳細的比較研究,這已提交的第三次年度國際臍血移植研討會在洛杉磯,加州, 6月3日至4日, 2005年。

For children without a related or unrelated donor, umbilical cord blood transplants are becoming a common treatment for children with high-risk ALL.兒童沒有一個相關或無關供者,臍血移植正成為一個共同的治療兒童與高風險所有。 Several reports have suggested that the results of umbilical cord blood transplants are as effective as transplants from unrelated donors.幾份報告建議的結果,臍血移植是有效的移植無關的捐助者。 Now, researchers have demonstrated that umbilical cord blood transplants are as effective as related donor transplants for the treatment of high-risk ALL.現在,研究表明,臍血移植是有效的作為有關捐助國移植用於治療高風險所有。

The current study compared the outcomes of children with high-risk ALL receiving HLA matched related transplants with those receiving umbilical cord blood transplants.目前的研究結果相比,兒童與高風險的所有接收的HLA匹配相關的移植與那些接受臍血移植手術。 Table 1 summarizes the main findings of this comparative study.表1概括了主要的結果,這比較研究。

These data add further to the data suggesting that umbilical cord blood is an acceptable source of stem cells for children with ALL.這些數據進一步補充到數據表明臍血是一個可以接受的幹細胞來源為兒童與所有。 The main importance of these observations is that a transplant can be performed much more rapidly when an umbilical cord blood transplant is performed than when an unrelated donor transplant is performed.主要的重要性,這些意見是,移植手術就可以執行更迅速地當一臍血移植是表現比當一個無關供者移植演出。 Since many children die or become too sick to be transplanted while waiting for an unrelated donor to be identified and set up for donation it would appear that umbilical cord blood would be a preferable choice for most high-risk children with ALL.由於許多兒童死於或變得太病假須移植的同時,等待一個無關供者加以確認和設立捐贈這樣看來,臍血將是一個最好的選擇,對於大多數的高風險兒童與所有。

Source來源


  • Umbilical Cord Blood Holds Clue to Childhood Allergies臍血舉行線索童年過敏
  • Stem Cell Research Provides Help for Children With High-Risk Brain Tumors幹細胞研究提供幫助的兒童與高風險的腦腫瘤
  • Information on Saving Lives through Umbilical Cord Blood信息對挽救生命,通過臍血
  • AML (Cancer) Treatment With Allogeneic Stem Cell Transplants Shows Strong Promise in Adults反洗錢(癌症)治療異基因造血幹細胞移植表明,強烈的承諾,在成年人
  • Cord Blood Transplantation: Treatment for Leukemia, Sickle Cell Anaemia etc.臍血移植:治療早幼粒細胞白血病,鐮狀細胞貧血等。
  • Umbilical Cord Blood Banking Supported by Royal College of Obstetricians and Gynaecologists臍帶血銀行的支持,英國皇家婦產科學院
  • Stem Cell Transplantation Provides Hope of Life from Leukemia to Elementary School Student造血幹細胞移植提供了希望的生活,從早幼粒細胞白血病,以小學生
  • Umbilical Cord Blood Transplant Better Than Bone Marrow Transplant in Leukemia Treatment for Children臍血移植優於骨髓移植在治療早幼粒細胞白血病兒童
  • Newborn Babies Saves Life With Umbilical Cord Blood Donation新生嬰兒的生命與保存臍帶血捐贈
  • Reovirus Used To Eliminate Cancer Cells From Autologous Stem Cell Transplants呼腸孤病毒用來消除癌細胞從自體造血幹細胞移植