Research team led by Yann Barrandon at the EPFL (Ecole Polytechnique Federale de Lausanne) and the CHUV (Lausanne University Hospital) has discovered, using animal model, that certain cells (clonogenic keratinocytes) inside hair follicles are true multipotent stem cells , capable of developing into the many different cell types needed for hair growth and follicle replacement.領導的研究小組，由李燕barrandon在epfl （的Ecole理工大學federale德洛桑）和chuv （洛桑大學醫院）發現，使用動物模型，某些細胞（角朊細胞克隆）內的毛囊是真正的多能幹細胞 ，能夠發展到許多不同類型的細胞所需要的毛髮生長及卵泡更換。

They demonstrate that these holoclones can be used for long-term follicle renewal.他們表明這些holoclones可用於長期卵泡重建。

Previously Barrandon (in 2001) was part of a French research team who reported in the Cell Journal that stem cells could be used to generate skin containing hair and sebaceous glands in mice.以前barrandon （ 2001年）的一個組成部分，法國研究小組報告了在細胞雜誌說，幹細胞可以用來生成皮膚含有頭髮和皮脂腺的影響。 At that time it was unclear whether the stem cells in hair follicles were true stem cells, capable of long-term renewal, or multipotent progenitor cells that would not permanently engraft in the follicle.在這個時間現在還不清楚是否有幹細胞在毛囊真正的幹細胞，能夠長期重建，或者多祖細胞不會永久engraft在卵泡。

In the current PNAS study, the Swiss researchers have answered that question, using rat whisker hair follicles to demonstrate that the clonogenic keratinocytes in hair follicles are true stem cells.在目前的pnas研究，瑞士研究人員已經回答了這個問題，用大鼠晶須毛囊表明，克隆角質形成細胞在毛囊是真正的幹細胞。

“With the progeny of a single stem cell, it would be theoretically possible to generate the complete hair bulb of a human being, and one that would last for years,” explains Barrandon. “與後代一個單一的幹細胞，便在理論上可能產生完整的頭髮燈泡一個人，一個將持續多年， ”解釋barrandon 。

The ability of the stem cells in hair follicles to repeatedly regenerate all the different cell types of the follicle and sebaceous glands has important implications for regenerative medicine.能力的幹細胞在毛囊反复再生的所有不同細胞類型的卵泡和皮脂腺具有重要意義再生醫學。 The method could one day be used to regenerate hair on patients with severe burns.該方法可以一天被用來再生頭髮，對患者嚴重燒傷。 This study is a logical complement to other work in Barrandon’s Laboratory of Stem Cell Dynamics, recognized for research into the reconstruction of injured tissues and organs.這項研究是一個合乎邏輯的補充，其他工作在barrandon的實驗室幹細胞動力學，公認的研究重建受傷的組織和器官。

Source: October 3rd Advance online edition of the Proceedings of the National Academy of Sciences資料來源： 10月3日推進網絡版的Proceedings of the National Academy of Sciences的