Multipotent Adult Stem Cells Discovered in Human Hair Follicles多能成體幹細胞的發現在人類毛囊
Researchers at the University of Pennsylvania School of Medicine have isolated a new source of adult stem cells that appear to have the potential to differentiate into several cell types.研究人員在賓夕法尼亞大學醫學院的孤立一個新的來源,成人幹細胞似乎有可能分化成幾種類型的細胞。
If their approach to growing these cells can be scaled up and proves to be safe and effective in animal and human studies, it could one day provide the tissue needed by an individual for treating a host of disorders, including peripheral nerve disease, Parkinson’s disease, and spinal cord injury.如果他們的做法越來越多,這些細胞能形成規模,並證明是安全的和有效的,在動物和人類的研究,它可以一天提供組織所需要的是個別治療一系列疾病,包括周圍神經疾病,帕金森病和脊髓損傷。
Hair follicles are well known to be a source for adult stem cells.毛囊是眾所周知的一個來源的成人幹細胞。 Using human embryonic stem cell culture conditions, the researchers isolated and grew a new type of multipotent adult stem cell from scalp tissue obtained from the National Institute of Health’s Cooperative Human Tissue Network.利用人類胚胎幹細胞培養條件下,研究人員分離,並增加了一種新型的多能成人幹細胞從頭皮組織,從國家衛生研究所的合作人類組織網絡。
The mutipotent stem cells grow as masses the investigators call hair spheres.該mutipotent幹細胞成長為群眾辦案人員呼籲頭髮各個領域。 After growing the “raw” cells from the hair spheres in different types of growth factors, the investigators were able to differentiate the stem cells into multiple lineages, including nerve cells, smooth muscle cells, and melanocytes (skin pigment cells).之後,越來越多的"原始"細胞從毛髮領域中不同類型的生長因子,調查人員能夠區分幹細胞分化成多種譜系,包括神經細胞,平滑肌細胞及黑素細胞(皮膚色素細胞) 。
Overall, the researchers showed that human embryonic stem cell media could be used to isolate and expand a novel population of multipotent adult stem cells from human hair follicles.總體而言,研究表明人類胚胎幹細胞可利用媒體來孤立和擴大了一種新型的人口多能成人幹細胞從人類毛囊。
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