A common chemical used in the manufacturing and pharmaceutical industries can repair damage to cardiac muscle cell membranes and prevent heart failure in mice with the genetic mutation that causes Duchenne muscular dystrophy, according to scientists at the University of Michigan Medical School. 1常用危險化學品的使用在製造業和製藥業可以修復受損的心臟肌肉細胞膜和防止心臟衰竭在小鼠與基因突變，導致Duchenne型肌營養不良症，據科學家在密歇根大學醫學院。

The mutation in the dystrophin gene causes the progressive deterioration of skeletal muscles seen in people with MD.突變，在肌營養不良蛋白基因的原因逐步惡化，骨骼肌看到，在人民有MD 。 But the mutation affects cardiac muscle, too.但突變的影響心肌，太。 Many people with Duchenne muscular dystrophy die in their 20s from heart failure caused by cardiomyopathy, a gradual weakening of the heart muscle.很多人與Duchenne型肌營養不良症死在20多歲，從心臟衰竭所造成的心肌病，逐漸削弱了心臟肌肉。 Heart failure is the second leading cause of death in DMD.心力衰竭是第二個主要死亡原因，在多哈部長宣言。

The chemical sealant that protected hearts in dystrophic mice from damage is called poloxamer 188.化學密封膠，保護心，在營養不良小鼠的損害是所謂的泊洛沙姆188 。 According to Joseph M. Metzger, Ph.D., the UM scientist who directed the research, poloxamer 188 can insert itself into small holes in cell membranes just like “a finger in a dike”.根據約瑟夫米梅茨格，博士研究生，這個科學家誰指示研究，泊洛沙姆188可以插入到本身的小孔，在細胞膜上，就像“用手指在一個堤防” 。

The UM study will be published July 17 in Nature as an advance online publication.在這個研究會出版的7月17日在性質上作為一個預先在線出版物。

“If issues of dosing and long-term safety can be resolved, our research suggests that poloxamer 188 could be a new therapeutic agent for preventing or limiting progressive damage to the hearts of patients with muscular dystrophy,” Metzger, a professor of molecular and integrative physiology and of internal medicine in the UM Medical School, says. “如果問題的配料和長期安全性可以得到解決，我們的研究表明，泊洛沙姆188可能是一種新的治療劑為防止或限制的逐步損害的心，患者肌肉萎縮症” ，梅茨格，教授分子和一體化生理學和醫學內部，在這個醫學院，說。

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