イギリスの科学者は自身の鼻の茎細胞との無力にされた脊髄の傷害の処置のための希望を提供する
最初のイギリスは教授大学大学ロンドンの背骨修理単位のディレクターによってGeoffrey Raisman、発表された彼らの自身の鼻の茎細胞と無力にされた脊髄の傷害の患者を扱うように試みる。 そのような移植は試みられたことこれが最初に間、研究は、より早い努力とは違って、動物の研究の40年プログラムで休み、確立された科学的な系統があるので驚くべきである。
新しい希望は発見で神経線維が大人の生命中の連続的な成長の状態にある神経系のたった1部があること休む。 神経は鼻の上にあり、嗅覚にかかわっている。
Raisman's教授のチームは鼻の女王の正方形、中央ロンドンの神経学そして神経外科のための国民の病院で試験調査の少なくとも10人の患者を来年早々扱うために細胞を収穫する。
「私は脊髄の傷害のための処置を見つけることを試みることの私の研究のキャリアを使い私が始まったときに私達がこれに遠い」、彼を言った得ることを決して予想しなかった。
彼は1日の移植は患者が失ったこと動く機能の多くを取り戻すことを可能にすることを信じる。
paraplegicの患者のためにこれは感覚のリターンをもたらし、ある足筋肉への動きは、動きを立て、もっと簡單にするように可能性としてはそれらがしてがtetraplegics (首の地域で高い脊髄の怪我と)、手の接触感覚そして動きを回復でき彼ら自身に服を着せ、与え、きれいにする機能を取り戻す。
「彼が患者の半分のまわりでそれを回復を幾分作ってもいい指摘したが、多くの年の間これらの傷害は不治と考慮され、まだである不治」、ある教授を言ったRaisman。 「人のためにこれはこれらの傷害の修理に開けるドアを」。
In the first human trial he will focus on patients - mostly teenagers - who have had an injury typical of motorcycle accidents where nerves in the arm have been pulled out of the spinal cord, leading to complete paralysis and loss of sensation in the arm as well as intractactable pain in most cases.
Depending on where the spine was severed in laboratory animals these transplants resulted in the ability to reach with a paw or to climb. “We were the first, and still the only, team to show that this repair resulted in a restoration of the ability to breathe,” he added. The principle could be used to restore bladder, bowel and sexual functions.
Making a patient his own donor “will avoid the need to use embryonic tissue, to find donor individuals, foreign stem cells, the immune response or to use powerful designer drugs with unknown side-effects.”
“Success will open the door to a number of other conditions where nerve fibres are damaged,” he said. “These include some major forms of stroke, as well as blindness and deafness caused by nerve injuries.
“We do not wish to raise false hopes in patients who are living with spinal cord injury. However, our work to date clearly indicates that, contrary to received wisdom, the spinal cord does have the potential to repair itself.”
First results are expected within the year.
Source
I am looking forward to hear positive news from this trial.
Filed under Spinal Cord Injury, Stem Cell |
November 30th, 2005 at 4:47 pm
Hope for spinal cord injuries courtesy of adult stem cells
Read this entry of the Stem Cell Blog about a new trial in England where spinal cord injury patients will be treated with their own nasal stem cells.
December 2nd, 2005 at 11:53 am
Respected sir
I suffered a major spinal cord injury last year and totally paralysed in my lower part.Is there any hope for me,as my parents are dependent on me.
December 5th, 2005 at 11:36 am
Hi Suprabha,
There are several encouraging news worldwide wrt. spinal cord injury treatment. I try to cover the important spinal cord injury news in this blog.
In God’s world there is always hope.
December 5th, 2005 at 2:44 pm
I also look forward to have use of adult stem cells rather than using the embryonic stem cells. It is well known that the embryonics are the most potent among stem cell research. However, considering the hot debates over moral and ethical issues I think we should keep seeking for cures in adult stem cells, as these British scientists did.
December 5th, 2005 at 11:34 pm
I think you cannot just abandon a possible medical revolution. You must invest in all areas, and when you acheive a breakthrough, we can then devote our resources to something specific. We cannot just reserve ourself to perfecting what we already have, because expansion into other fields is always the best decision. Expanding gives us more options as to how we approach very difficult medical problems.
December 5th, 2005 at 11:42 pm
ISH,
> However, considering the hot debates over moral and ethical issues I think we should keep seeking for cures in adult stem cells, as these British scientists did.
Adult stem are very limited in their potential in comparison with embryonic stem cell as you have correctly surmised.
Do you think it is proper to allow dubious ethical arguments to prevent scientists to find cure for hundreds of life-threatening and debilitating diseases through embryonic stem cell research?
Scientists all throughtout the ages have fought with narrow religious agendas to promote the cause of science. I think it is right time for them to step forward and fight again for the greatest cause of saving millions of human lives.
February 12th, 2006 at 10:47 pm
All avenues should be explored. Only that way will we know which works the best. It’s sad that Bush does his best to derail embryonic and cloning research by hysteria and self righteousness. He mentions the 30,000 Iraqi civilians killed without batting an eye, yet screams in horror about embryos being used on the cloning of a few cells. His hypocracy knows no limits.